Compound library storage underpins modern drug discovery, chemical biology, and screening-driven research. It refers to the controlled systems, conditions, and practices used to preserve collections ...
Introducing a new drug to a market has become an enormous undertaking because of expanding research and development costs, which are estimated at over one billion USD 1,2,3,4. With a view to reducing ...
The “one-bead-one-compound” (OBOC) combinatorial library method synthesizes millions of random compounds such that each bead displays only one compound. Bead libraries are screened, and positive beads ...
Potential inhibitors of a target biomolecule, NAD-dependent deacetylase Sirtuin 1, were identified by a contest-based approach, in which participants were asked to propose a prioritized list of 400 ...
Protein–protein interactions (PPIs) are recognized as important targets in drug discovery. The characteristics of molecules that inhibit PPIs differ from those of small-molecule compounds. We ...
How to choose the compound library? We know that the chemical space is endless. However, the good news is that there is no need to have a library with billions of compounds. There are many ways by ...
Even before companies spend exorbitant amounts on clinical trials (most of which fail), they already have spent significant time and money identifying the best drug candidates for those trials.
Recursion Pharmaceuticals. has filed a patent for a computer system that identifies a subset of compounds through high throughput screening in various cell contexts. The system obtains vectors for ...
Browse the complete list of chemical compound collections available at HTB, ranging from broad diversity libraries to focused sets tailored for specific pathways, targets, and disease areas. 12 New ...
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