Despite extensive studies on DNA replication, the exchange mechanisms of DNA polymerase during replication remain unclear. Existing models propose that this exchange is facilitated by protein partners ...

Segmental copy-number gains are major contributors to human genetic variation and disease, but how these alterations arise remains incompletely understood. Here, based on the analyses of both ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

理化学研究所（理研）生命機能科学研究センター発生エピジェネティクス研究チームの平谷伊智朗チームリーダー、高橋沙央里基礎科学特別研究員、三浦尚研究員、三重大学大学院医学系研究科の竹林慎一郎講師、柴田隆豊大学院生（研究当時）らの共同 ...

The research also shows that upon differentiation, mouse ES cells adopt replication characteristics similar to those of non-pluripotent cells. Furthermore, some features of DNA replication observed in ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

From the blueprint of life encoded in our DNA to the awe-inspiring complexity of our genetic inheritance, we will embark on a journey through the microscopic world within us and witness the remarkable ...

DNA replication is happening continuously throughout the body, as many as trillions of times per day. Whenever a cell divides—whether to repair damaged tissue, replace old cells, or simply to help the ...

Revising the structure and replication of DNA? Test your knowledge of the process and need for DNA replication with this Higher Biology quiz.