Although the majority of patients are diagnosed with early-stage disease, outcomes remain poor for those with primary advanced or recurrent endometrial cancer, with reported 5-year survival rates as ...

Mismatch repair (MMR) deficiency occurs in 10–20% of colorectal cancer (CRC) cases, leading to microsatellite instability (MSI). Although MSI/MMR testing is critical for CRC management, high costs and ...

Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline pathogenic variants of DNA mismatch repair (MMR) genes. To diagnose LS, the microsatellite instability (MSI) test ...

NORTHFIELD, Ill.--(BUSINESS WIRE)--Recognizing a need for evidence-based recommendations to guide molecular testing in the management of patients with cancer, the College of American Pathologists (CAP ...

根治切除可能な大腸癌に対する術前MMR/MSI検査の実施率は普及啓発活動後で30％未満にとどまり、検査の意義に対するリテラシーの向上や、術前MMR/MSI検査を実施するフローの構築が重要な課題であることが示された。