Definition: Non-coding RNA (ncRNA) is any RNA molecule that is transcribed from DNA but is not translated into a protein. Instead of serving as a protein blueprint, the RNA molecule itself is the ...

Bacteria employ small non-coding RNAs (sRNAs) as versatile regulators of gene expression, primarily by modulating the activity of RNA polymerase and its interaction with sigma factors. These sRNAs, ...

The low quantitative accuracy of conventional small noncoding RNA sequencing (sncRNA-seq) methods due to extensive ligation bias commonly limits functional investigation of microRNAs (miRNAs) and PIWI ...

Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may influence how long a person lives. Investigators evaluated 828 small ...

An interdisciplinary and international research group led by Dr. Volker Busskamp from the Center for Regenerative Therapies Dresden at the TU Dresden (CRTD) has decoded the regulatory impact on ...

Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may influence how long a person lives. Investigators evaluated 828 small ...

Small RNA therapeutics can modulate multiple genes. This ability may counter tumor adaptation and resistance, overcoming the ...

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to ...

Historically, drug discovery has centred around proteins but as targets become increasing saturated, novel RNA-targeting drugs indicate potential in rare diseases and oncology. Photo by Christoph ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...